From September 13th to 15th, an impressive "big show" took place at the Beijing International Exhibition Center, with membrane technology as its central theme. The event, the 2006 China International Film Industry Exhibition organized by the China Petroleum and Chemical Industry Association and the China Film Industry Association, attracted over 100 domestic and international companies in the film and technology sectors. Visitors flooded the venue, eager to explore the latest advancements in membrane technology.
At the exhibition, reporters observed a variety of new membrane technologies and equipment specifically designed for pharmaceutical production. Experts highlighted that, with increasing demands for higher drug quality and lower production costs, membrane techniques such as ultrafiltration, pervaporation, and membrane distillation have become key players in the medical field. These technologies help address challenges in extraction, separation, concentration, and purification, significantly improving the overall efficiency and standards of pharmaceutical manufacturing.
Ultrafiltration has made significant progress in recent years, particularly in solving critical issues like depyrogenation in injectable drugs. Traditionally, activated carbon adsorption was used, but it was labor-intensive and led to low yields. Ultrafiltration, on the other hand, effectively removes pyrogens without compromising product quality. Researchers from Beijing University of Traditional Chinese Medicine demonstrated that ultrafiltration improved the baicalin content in Qingkailing injection, resulting in a lighter color and fewer particles. Similarly, the Chinese Academy of Pharmacy used ultrafiltration to prepare three compound Chinese herbal injections, achieving excellent clarity and stability over time.
In addition, ultrafiltration is widely applied in antibiotic production. For example, Merck uses ultrafiltration membranes with a molecular weight cut-off of 24,000 to filter cephalosporin fermentation broth, leading to a 2% yield increase and a 2/3 reduction in material costs. Penicillin manufacturers also benefit from using ultrafiltration to remove impurities, eliminating the need for toxic demulsifiers and simplifying the process.
Pervaporation, another emerging membrane technology, is gaining traction due to its energy-saving advantages. It separates components based on differences in solubility and diffusion within liquid mixtures. Companies like Harbin Pharmaceutical and Shenyang Dongrui have successfully implemented this technique for ethanol dehydration and t-butanol dewatering, achieving significant economic benefits.
Membrane distillation, which uses hydrophobic microporous membranes to separate solutions at different temperatures, offers unique advantages for heat-sensitive substances. It allows for high-concentration processing at lower temperatures, making it ideal for applications such as penicillin concentration and the purification of traditional Chinese medicine extracts. This technology ensures minimal loss of active ingredients while maintaining high efficiency and purity.
Overall, membrane technology continues to revolutionize the pharmaceutical industry, offering sustainable, efficient, and innovative solutions that meet modern production demands.
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Pump Part Description | Material | Application |
Impeller, liner, throat bush etc. | High chrome, Ceramic | For mines and other wear resistance working conditions |
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Cover plate, frame plate, base, bearing housing, etc. | Grey iron and ductile iron | All kinds of working conditions |
Expeller, expeller ring, stuffing box, etc. | Stainless steel, high chrome | Chemical industry, corrosion (especially for acid) conditions |
Shaft, shaft sleeve, lantern ring, neck ring, etc. | Stainless steel, 1045 steel |
|
Seal, O ring | Elastomer |
|
Bolt | Stainless steel, 1045 steel |
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SHIJIAZHUANG MUYUAN INDUSTRY & TRADE CO., LTD. , https://www.cnmuyuan.com